CYMO Use Case
Empowering Developers, Researchers, and Data Scientists in Building XAI-Powered Models

Digital Biomarkers for Brain and Mental Health

Unlock the potential of CYMO to create advanced, explainable AI models that harness digital biomarkers for improved brain and mental health diagnostics and monitoring.

Digital Biomarkers for Brain and Mental Health

Extract Digital Biomarkers with CYMO in Action

Uncover Subtle Signals

Uncover subtle statistical signals in verbal behavior from speech or text associated with neurodegenerative and psychiatric disorders

Trust in Rigorous Validation

Benefit from digital biomarkers that undergo rigorous computational validation, ensuring reliable association with pathogenic states.

Enhance Classification and Predictive Models

Build advanced predictive models for early and accurate detection of disorders, trained on CYMO-powered digital biomarkers.

Monitor and Track Disease Progression

Harness CYMO's powerful features to accurately monitor and track disease progression over time.

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Digital biomarkers are set to revolutionize healthcare, driving groundbreaking advancements in disease prevention, diagnostics, treatment, and monitoring.

DEFINITION OF A DIGITAL BIOMARKER

A digital biomarker is an objective, quantifiable measure of physiology and/or behavior, serving as an indicator of biological, pathological processes, or responses to exposure or intervention, derived from digital measurements and subjected to rigorous computational validations.

To dive deeper into this topic, explore our scientific research publications.

Why Language-Based Digital Biomarkers?

Language-based digital biomarkers enable objective, scalable, ecologically valid, and long-term monitoring through frequent or continuous assessment that is minimally obtrusive and can operate in the background of everyday activities.

In contrast to blood and imaging biomarkers that measure elevated levels of tau and amyloid proteins, language-based digital biomarkers are highly sensitive to early cognitive changes, detecting these alterations long before structural changes become apparent on neuroimaging.

Language impairments and dysfunctions exhibit unique patterns across diverse disorders, aiding in differential diagnosis and offering a clearer understanding of an individual’s mental health status.

Comparison of Language-Based Digital Biomarkers:

This table evaluates language-based digital biomarkers derived from spontaneous speech and writing against blood and imaging biomarkers and clinical rating scales used in neurodegenerative and psychiatric diagnostics.

Language-Based Digital BiomarkersBlood BiomarkersImaging BiomarkersClinical (Rating) ScaleEdit
Scalable

Cost-effective

Non-obstrusive

Patient compliance

Predictiveness

Why Digital Biomarkers by Exaia?

Rigorous Scientific Validation

Exaia's digital biomarkers are validated through peer-reviewed research, demonstrating strong predictive power for diverse neurodegenerative and psychiatric disorders

Alzheimer's Disease
Depression
Bipolar Disorder
Anxiety
Stress
Social Anxiety Disorder
ADHD

Superior Performance

The ML models consistently outperform benchmarks and excel in international shared task competitions, showcasing their reliability and effectiveness.

Detection of Alzheimer's Dementia

F1 score of 83.07% at 2021 ADReSSo challenge organized by Carnegie Mellon University.

Detection of Chronic Stress

F1 75.8% at SMM4H Shared Task 2022 organized by Roche Innovation Center & Cedars-Sinai Medical Center.

Detection of Social Anxiety

F1 83.8% at SMM4H Shared Task 2023 organized by Roche Innovation Center & University of Pennsylvania at AMIA2023.

End-to-End Platform

Exaia is the only fully scientifically validated platform for the automatic extraction of digital biomarkers, capturing the multidimensional nature of verbal behavior, including the impact of automatic speech recognition (ASR) on downstream tasks and precise high-resolution measurements of expert-engineered indicators.

In-House Developed Tools

Our powerful analytics tools are entirely developed in-house, giving us unmatched control, flexibility, and security. By eliminating reliance on closed-source third-party software, we deliver a fully customizable, transparent, and adaptable solution tailored to meet the unique demands of our platform.

How it works

Exaia's Human-Centric and Explainable Artificial Intelligence (HCXAI) Platform

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HCXAI platform
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High-Precision Measurements of Digital Biomarkers.

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Confidence Scores for Detected Mental Health Conditions.

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Model Explainations for insights into Decision-Making Processes.

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Join Us in Our Mission to Transform Healthcare with Trustworthy AI and Digital Biomarkers

We invite researchers, clinicians, and healthcare leaders to collaborate with us in advancing a shared vision: developing objective, scalable, and non-intrusive AI solutions that leverage digital biomarkers derived from spontaneously produced speech and language. Through trustworthy AI, we aim to drive early detection, precise diagnostics, and continuous monitoring for conditions such as Alzheimer's disease, dementia, depression, bipolar disorder, generalized anxiety disorder, ADHD, and autism.

Collaborative Opportunities with Exaia's Digital Biomarkers

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Early Detection & Risk Assessment

Identify patients with early susceptibility to neurodegenerative and psychiatric conditions, facilitating timely intervention.

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Precision Diagnostics & Comorbidity Management

Harness biomarkers to accurately differentiate diagnoses in cases with overlapping symptoms, facilitating effective management of comorbid conditions and enhancing overall diagnostic accuracy.

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Monitoring Disease Progression & Treatment Efficacy

Continuously assess disease progression and treatment impact over time, ensuring adaptive care and long-term management.

Testimonials

“Exaia's trustworthy AI, leveraging digital biomarkers and machine learning, has transformed our approach to Alzheimer’s disease. Their innovative technology enables precise tracking of disease progression and responses to transcranial pulse stimulation therapy, allowing us to make informed clinical decisions and enhance patient outcomes.”
Avartar of Dr. Ali Riza Grünen

Dr. Ali Riza Günes

Senior Physician Center for Neurostimulation AJK-Neuss